Highly diastereoselective synthesis of anti-gamma-N-benzylamino-beta-hydroxyphosphonates
The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates.
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2004-03 (6), p.672-673 |
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creator | Ordóñez, Mario de la Cruz-Cordero, Ricardo Quiñónes, Citlali González-Morales, Angelina |
description | The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates. |
doi_str_mv | 10.1039/b316262a |
format | Article |
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source | Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Benzylamines - chemical synthesis Benzylamines - chemistry Molecular Conformation Organophosphorus Compounds - chemical synthesis Organophosphorus Compounds - chemistry Stereoisomerism |
title | Highly diastereoselective synthesis of anti-gamma-N-benzylamino-beta-hydroxyphosphonates |
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