Highly diastereoselective synthesis of anti-gamma-N-benzylamino-beta-hydroxyphosphonates

The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2004-03 (6), p.672-673
Hauptverfasser: Ordóñez, Mario, de la Cruz-Cordero, Ricardo, Quiñónes, Citlali, González-Morales, Angelina
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container_issue 6
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container_title Chemical communications (Cambridge, England)
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creator Ordóñez, Mario
de la Cruz-Cordero, Ricardo
Quiñónes, Citlali
González-Morales, Angelina
description The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates.
doi_str_mv 10.1039/b316262a
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source Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Benzylamines - chemical synthesis
Benzylamines - chemistry
Molecular Conformation
Organophosphorus Compounds - chemical synthesis
Organophosphorus Compounds - chemistry
Stereoisomerism
title Highly diastereoselective synthesis of anti-gamma-N-benzylamino-beta-hydroxyphosphonates
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