Highly diastereoselective synthesis of anti-gamma-N-benzylamino-beta-hydroxyphosphonates

The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2004-03 (6), p.672-673
Hauptverfasser:	Ordóñez, Mario, de la Cruz-Cordero, Ricardo, Quiñónes, Citlali, González-Morales, Angelina
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzylamines - chemical synthesis Benzylamines - chemistry Molecular Conformation Organophosphorus Compounds - chemical synthesis Organophosphorus Compounds - chemistry Stereoisomerism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The reduction of gamma-N-benzylamino-beta-ketophosphonates derived from readily available amino acids can be carried out stereoselectively with Zn(BH(4))(2) at -78 degrees C to produce the anti-gamma-amino-beta-hydroxyphosphonates.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/b316262a