Description of a novel HLA-DRB1 allele, DRB11207

: A new DRB1 allele has been identified during routine HLA‐DRB1 generic typing with sequence specific oligonucleotides. The new allele was confirmed by PCR‐restriction fragment length polymorphism analysis and subsequently sequenced. This showed the novel allele, named HLA‐DRB1*1207, was similar in...

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Veröffentlicht in:	Tissue antigens 2002-02, Vol.59 (2), p.162-164
Hauptverfasser:	Dunckley, H., Le, T., Dodd, R., Hogbin, J.-P., Strickland, J., Chapman, G., Greville, W.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Base Sequence DRB11207 HLA-DR Antigens - genetics HLA-DR Antigens - immunology HLA-DRB1 HLA-DRB1 Chains Humans Molecular Sequence Data Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology, Nucleic Acid
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	: A new DRB1 allele has been identified during routine HLA‐DRB1 generic typing with sequence specific oligonucleotides. The new allele was confirmed by PCR‐restriction fragment length polymorphism analysis and subsequently sequenced. This showed the novel allele, named HLA‐DRB11207, was similar in sequence to DRB112011, except for codon 69 of exon 2.
ISSN:	0001-2815 1399-0039
DOI:	10.1034/j.1399-0039.2002.590220.x