The permeability transition pore complex: another view

Mitochondria play a critical role in initiating both apoptotic and necrotic cell death. A major player in this process is the mitochondrial permeability transition pore (MPTP), a non-specific pore, permeant to any molecule of

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Bibliographische Detailangaben
Veröffentlicht in:	Biochimie 2002-02, Vol.84 (2), p.153-166
Hauptverfasser:	Halestrap, Andrew P, McStay, Gavin P, Clarke, Samantha J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine nucleotide translocase Animals Calcium Calcium - metabolism Cell Membrane Permeability Cyclophilin-D Cyclophilins - physiology Formicidae Humans Ion Channels - physiology Mitochondria - physiology Mitochondrial Membrane Transport Proteins Mitochondrial Permeability Transition Pore Mitochondrial swelling Models, Molecular MPTP mechanism Oxidative stress Peptidyl-Prolyl Isomerase F Reconstitution Voltage activated anion channel
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Beschreibung
Zusammenfassung:	Mitochondria play a critical role in initiating both apoptotic and necrotic cell death. A major player in this process is the mitochondrial permeability transition pore (MPTP), a non-specific pore, permeant to any molecule of
ISSN:	0300-9084 1638-6183
DOI:	10.1016/S0300-9084(02)01375-5