The Exceptional Glutathione Peroxidase-Like Activity of Di(3-hydroxypropyl) Selenide and the Unexpected Role of a Novel Spirodioxaselenanonane Intermediate in the Catalytic Cycle

A new mechanism for reducing oxidative stress: Di(3‐hydroxypropyl) selenide has exceptionally high glutathione peroxidase‐like catalytic activity in the reduction of tert‐butyl hydroperoxide with benzyl thiol. The catalytic cycle proceeds via a novel spirodioxaselenanonane, which was isolated and ch...

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Veröffentlicht in:	Angewandte Chemie International Edition 2004-02, Vol.43 (10), p.1268-1270
Hauptverfasser:	Back, Thomas G., Moussa, Ziad, Parvez, Masood
Format:	Artikel
Sprache:	eng
Schlagworte:	oxidative stress peroxidases selenium spiro compounds thiols
Online-Zugang:	Volltext
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