Results of early reevaluation of growth hormone secretion in short children with apparent growth hormone deficiency

Objective: To test the hypothesis that normalization of the growth hormone (GH) response to stimulation in patients with GH deficiency (GHD) and normal magnetic resonance imaging (MRI) of the hypothalamic-pituitary area might occur earlier than at attainment of final height. Study design: Prepuberta...

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Veröffentlicht in:	The Journal of pediatrics 2002-04, Vol.140 (4), p.445-449
Hauptverfasser:	Loche, Sandro, Bizzarri, Carla, Maghnie, Mohamad, Faedda, Antonella, Tzialla, Chryssoula, Autelli, Michele, Casini, Maria Rosaria, Cappa, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Body Height - physiology Child Child Welfare Child, Preschool Endocrinology Female Growth Disorders - physiopathology Human Growth Hormone - blood Human Growth Hormone - deficiency Human Growth Hormone - secretion Humans Hypothalamus - metabolism Insulin-Like Growth Factor I - metabolism Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging Male Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pituitary Gland - metabolism Predictive Value of Tests Statistics as Topic Time Factors
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Beschreibung
Zusammenfassung:	Objective: To test the hypothesis that normalization of the growth hormone (GH) response to stimulation in patients with GH deficiency (GHD) and normal magnetic resonance imaging (MRI) of the hypothalamic-pituitary area might occur earlier than at attainment of final height. Study design: Prepubertal children with short stature (21 boys and 12 girls; age, 5.2-10 years), in whom a diagnosis of GHD was based on a GH response
ISSN:	0022-3476 1097-6833
DOI:	10.1067/mpd.2002.122729