Gamma-hydroxybutyrate increases tryptophan availability and potentiates serotonin turnover in rat brain

Gamma-hydroxybutyrate (GHB) is both a therapeutic agent and a recreative drug. It has sedative, anxiolytic and euphoric effects. These effects are believed to be due to GHB-induced potentiation of cerebral GABAergic and dopaminergic activities, but the serotonergic system might also be involved. In...

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Veröffentlicht in:Life sciences (1973) 2002-03, Vol.70 (18), p.2101-2112
Hauptverfasser: Gobaille, Serge, Schleef, Carmen, Hechler, Viviane, Viry, Sandrine, Aunis, Dominique, Maitre, Michel
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Sprache:eng
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