Palladium-Catalyzed Enantioselective Allylic Phosphination

Palladium-Catalyzed Enantioselective Allylic Phosphination

A new cat. for chiral phosphines: A highly enantioselective allylic phosphination reaction is realized using the Pd–Josiphos(L) catalyst system. This CP bond forming reaction provides a new access to chiral phosphines (see scheme) that may be further functionalized. Cy=cyclohexyl, dba=trans,trans‐d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2008-06, Vol.47 (26), p.4878-4881
Hauptverfasser: Butti, Pietro, Rochat, Raphaël, Sadow, Aaron D., Togni, Antonio
Format: Artikel
Sprache:eng
Schlagworte:
allylation
allylic phosphination
asymmetric catalysis
palladium
phosphane ligands
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A new cat. for chiral phosphines: A highly enantioselective allylic phosphination reaction is realized using the Pd–Josiphos(L) catalyst system. This CP bond forming reaction provides a new access to chiral phosphines (see scheme) that may be further functionalized. Cy=cyclohexyl, dba=trans,trans‐dibenzylideneacetone.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200801287