Pharmaceutical prospects for RNA interference

RNA interference has proven to be a powerful tool in gene function validation. Recently, the first studies were published reporting a disease-modulating activity of the technique, suggesting a promise for RNA interference as a novel therapeutic strategy. This review discusses the recent advancements...

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Veröffentlicht in:	Pharmaceutical research 2004-01, Vol.21 (1), p.1-7
Hauptverfasser:	Schiffelers, Raymond M, Woodle, Martin C, Scaria, Puthupparampil
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Delivery Systems - methods Drug Delivery Systems - trends Humans RNA Interference - physiology RNA, Small Interfering - chemical synthesis RNA, Small Interfering - chemistry Technology, Pharmaceutical - methods Technology, Pharmaceutical - trends
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Beschreibung
Zusammenfassung:	RNA interference has proven to be a powerful tool in gene function validation. Recently, the first studies were published reporting a disease-modulating activity of the technique, suggesting a promise for RNA interference as a novel therapeutic strategy. This review discusses the recent advancements in realizing the clinical utility of RNA-interference.
ISSN:	0724-8741 1573-904X
DOI:	10.1023/B:PHAM.0000012145.49054.6c