Gianotti-Crosti Syndrome in Two Adult Patients
Background: Gianotti-Crosti syndrome was first described in Italy by Gianotti in 1955. It is considered a benign, self-limited exanthem that occurs in younger children. Adult cases are rare. Objective: We report two cases of Gianotti-Crosti syndrome in a previously healthy 37-year old Asian and 21-y...
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Veröffentlicht in: | Journal of cutaneous medicine and surgery 2008-05, Vol.12 (3), p.121-125 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background:
Gianotti-Crosti syndrome was first described in Italy by Gianotti in 1955. It is considered a benign, self-limited exanthem that occurs in younger children. Adult cases are rare.
Objective:
We report two cases of Gianotti-Crosti syndrome in a previously healthy 37-year old Asian and 21-year old Caucasian female.
Methods/Results:
Histopathological analysis of 4-mm punch biopsies from the upper extremity of both patients revealed an interstitial dermatitis with mild to moderate perivascular lymphocytic infiltrate and occasional scattered eosinophils in the superficial and mid-dermis. Clinicopathological correlation was consistent with Gianotti-Crosti syndrome.
Conclusion:
Since both patients experienced significant pruritus, patient 1 was initially treated with a high potency topical corticosteroid followed by a two-week course of oral prednisone and patient 2 was treated with a potent topical corticosteroid. Both patients were asymptomatic at follow-up 3 to 4 weeks after their initial presentation. |
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ISSN: | 1203-4754 1615-7109 |
DOI: | 10.2310/7750.2007.00044 |