The value of lymphocytopenia as a marker of systemic involvement in cutaneous lupus erythematosus

The value of lymphocytopenia as a marker of systemic involvement in cutaneous lupus erythematosus

Summary Background  Some patients suffering from cutaneous lupus erythematosus (CLE) develop extracutaneous manifestations during the course of the disease: up to 5% of patients with discoid LE (DLE) and up to 30% of subacute cutaneous LE (SCLE) patients show systemic involvement. Recent studies rev...

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Veröffentlicht in:British journal of dermatology (1951) 2002-05, Vol.146 (5), p.869-871
Hauptverfasser: Wenzel, J., Bauer, R., Uerlich, M., Bieber, T., Boehm, I.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
cutaneous lupus erythematosus
Female
Hematologic and hematopoietic diseases
Humans
Lupus Erythematosus, Cutaneous - blood
Lupus Erythematosus, Cutaneous - complications
Lupus Erythematosus, Discoid - blood
Lupus Erythematosus, Discoid - complications
Lymphocyte Count
lymphocytopenia
Lymphopenia - etiology
Male
Medical sciences
Middle Aged
Other diseases. Hematologic involvement in other diseases
Prognosis
Retrospective Studies
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
systemic manifestation
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Zusammenfassung:Summary Background  Some patients suffering from cutaneous lupus erythematosus (CLE) develop extracutaneous manifestations during the course of the disease: up to 5% of patients with discoid LE (DLE) and up to 30% of subacute cutaneous LE (SCLE) patients show systemic involvement. Recent studies revealed some markers indicating systemic manifestations of CLE patients. However, the significance of diminished peripheral lymphocyte numbers as a marker of systemic involvement in CLE has not been investigated before. Objectives  To determine the value of lymphocytopenia (
ISSN:0007-0963
1365-2133
DOI:10.1046/j.1365-2133.2002.04588.x