Sequence Type and emm Type Diversity in Streptococcus pyogenes Isolates Causing Invasive Disease in Norway between 1988 and 2003

The incidence of invasive group A streptococcal disease has increased in Norway since the 1980s. Analysis of 100 isolates recovered from 1988 to 2003 showed an increased genotypic diversity over time, while the prevalence of the strain that dominated in 1988, sequence type (ST)-28/emm-1, decreased....

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Veröffentlicht in:	Journal of Clinical Microbiology 2008-06, Vol.46 (6), p.2102-2105
Hauptverfasser:	Meisal, Roger, Høiby, E. Arne, Aaberge, Ingeborg S, Caugant, Dominique A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Antigens, Bacterial - classification Antigens, Bacterial - genetics Bacterial Outer Membrane Proteins - classification Bacterial Outer Membrane Proteins - genetics Bacteriology Biological and medical sciences Carrier Proteins - classification Carrier Proteins - genetics Child Child, Preschool Epidemiology Fasciitis, Necrotizing - epidemiology Fasciitis, Necrotizing - microbiology Female Fundamental and applied biological sciences. Psychology Genetic Variation Genotype Humans Incidence Infant Male Microbial Sensitivity Tests Microbiology Middle Aged Miscellaneous Norway - epidemiology Sequence Analysis, DNA - methods Streptococcal Infections - epidemiology Streptococcal Infections - microbiology Streptococcus pyogenes Streptococcus pyogenes - classification Streptococcus pyogenes - drug effects Streptococcus pyogenes - genetics Streptococcus pyogenes - isolation & purification
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Zusammenfassung:	The incidence of invasive group A streptococcal disease has increased in Norway since the 1980s. Analysis of 100 isolates recovered from 1988 to 2003 showed an increased genotypic diversity over time, while the prevalence of the strain that dominated in 1988, sequence type (ST)-28/emm-1, decreased. Necrotizing fasciitis was often associated with ST-15/emm-3.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.00363-08