Antiretroviral Therapy for HIV-Infected Tuberculosis Patients Saves Lives but Needs to Be Used More Frequently in Thailand

INTRODUCTION:The impact of antiretroviral therapy (ART) on HIV-infected tuberculosis (TB) patients in public health programs in resource-limited settings is not well documented due to problems with statistical bias in observational studies. METHODS:We measured the impact of ART on survival of HIV-in...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2008-06, Vol.48 (2), p.181-189
Hauptverfasser:	Sanguanwongse, Natpatou, Cain, Kevin P, Suriya, Patcharin, Nateniyom, Sriprapa, Yamada, Norio, Wattanaamornkiat, Wanpen, Sumnapan, Surin, Sattayawuthipong, Wanchai, Kaewsa-ard, Samroui, Ingkaseth, Sakon, Varma, Jay K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged AIDS/HIV Anti-HIV Agents - therapeutic use Antiretroviral drugs Asian people Bacterial diseases Biological and medical sciences CD4 Lymphocyte Count Child Child, Preschool Drug therapy Female Fundamental and applied biological sciences. Psychology HIV HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology Human bacterial diseases Human immunodeficiency virus Human viral diseases Humans Infant Infectious diseases Male Medical sciences Microbiology Middle Aged Miscellaneous Mycobacterium Public health Thailand Tuberculosis Tuberculosis - mortality Tuberculosis and atypical mycobacterial infections Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology
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Zusammenfassung:	INTRODUCTION:The impact of antiretroviral therapy (ART) on HIV-infected tuberculosis (TB) patients in public health programs in resource-limited settings is not well documented due to problems with statistical bias in observational studies. METHODS:We measured the impact of ART on survival of HIV-infected TB patients in Thailand using a propensity score analysis that adjusted for factors associated with receiving ART. RESULTS:Of 626 HIV-infected TB patients started on ART during TB treatment, 68 (11%) died compared with 295/643 (46%) of patients not prescribed ART (relative risk 0.24, 95% confidence interval0.19 to 0.30); in patients with very low CD4 (
ISSN:	1525-4135 1944-7884
DOI:	10.1097/QAI.0b013e318177594e