Fluorescent Tetracycline Labeling as an Aid to Debridement of Necrotic Bone in the Treatment of Chronic Osteomyelitis

The authors have found that several months of preoperative tetracycline administration will label living bone so that it fluoresces under a blacklight during surgery. This allows intraoperative differentiation of viable bone from necrotic sequestra, which require removal in the treatment of chronic...

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Veröffentlicht in:	Journal of orthopaedic trauma 2002-05, Vol.16 (5), p.345-346
Hauptverfasser:	Dahners, Laurence E, Bos, Gary D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chronic Disease Debridement - methods Fluorescence Humans Indicators and Reagents Medical sciences Orthopedic surgery Osteomyelitis - complications Osteomyelitis - surgery Osteonecrosis - etiology Osteonecrosis - surgery Preoperative Care - methods Sensitivity and Specificity Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tetracycline - administration & dosage
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Beschreibung
Zusammenfassung:	The authors have found that several months of preoperative tetracycline administration will label living bone so that it fluoresces under a blacklight during surgery. This allows intraoperative differentiation of viable bone from necrotic sequestra, which require removal in the treatment of chronic bone infection.
ISSN:	0890-5339 1531-2291
DOI:	10.1097/00005131-200205000-00009