Role of transposable elements in trypanosomatids

Transposable elements constitute 2–5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as t...

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Veröffentlicht in:	Microbes and infection 2008-05, Vol.10 (6), p.575-581
Hauptverfasser:	Bringaud, Frédéric, Ghedin, Elodie, El-Sayed, Najib M.A., Papadopoulou, Barbara
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cellular function DNA Transposable Elements - physiology DNA, Intergenic - genetics Domestication Evolution Evolution, Molecular Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - physiology Genome, Protozoan - genetics Host-Parasite Interactions - physiology Leishmania Leishmania - genetics Leishmania - physiology Microbiology Regulation of mRNA stability Retroposon Transposable element Trypanosoma
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Beschreibung
Zusammenfassung:	Transposable elements constitute 2–5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.
ISSN:	1286-4579 1769-714X
DOI:	10.1016/j.micinf.2008.02.009