Randomized trial of tacrolimus versus cyclosporin microemulsion in renal transplantation

This study was undertaken to compare the efficacy and safety of tacrolimus (Tac) with the microemulsion formulation of cyclosporin (CyA) in children undergoing renal transplantation. A 6-month, randomized, prospective, open, parallel group study with an open extension phase was conducted in 18 cente...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2002-03, Vol.17 (3), p.141-149
Hauptverfasser:	TROMPETER, Richard, FILLER, Guido, KLARE, Bernd, ZACCHELLO, Graziella, BREKKE, Inge Bjorn, MCGRAW, Mary, PERNER, Ferenc, GHIO, Lucian, BALZAR, Egon, FRIMAN, Styrbjörn, GUSMANO, Rosanna, STOLPE, Jochen, WEBB, Nicholas J. A, WATSON, Alan R, MILFORD, David V, TYDEN, Gunnar, GRENDA, Ryszard, JANDA, Jan, HUGHES, David, EHRICH, Jochen H. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Biological and medical sciences Child Cyclosporine - therapeutic use Female Follow-Up Studies Graft Rejection Graft Survival Humans Immunomodulators Immunosuppressive Agents - therapeutic use Kidney Transplantation Male Medical sciences Pharmacology. Drug treatments Prospective Studies Tacrolimus - therapeutic use
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Beschreibung
Zusammenfassung:	This study was undertaken to compare the efficacy and safety of tacrolimus (Tac) with the microemulsion formulation of cyclosporin (CyA) in children undergoing renal transplantation. A 6-month, randomized, prospective, open, parallel group study with an open extension phase was conducted in 18 centers from nine European countries. In total, 196 pediatric patients (
ISSN:	0931-041X 1432-198X
DOI:	10.1007/s00467-001-0795-9