Increased myocardial expression of osteopontin in patients with advanced heart failure

The expression of the adhesion protein osteopontin (OP) is associated with cardiac hypertrophy and is significantly increased after transition to heart failure in experimental animal models. We, therefore, hypothesized that OP could be upregulated in heart failure in humans. In the present study, we...

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Veröffentlicht in:	European journal of heart failure 2002-03, Vol.4 (2), p.139-146
Hauptverfasser:	Stawowy, Philipp, Blaschke, Florian, Pfautsch, Peter, Goetze, Stephan, Lippek, Frank, Wollert-Wulf, Brigitte, Fleck, Eckart, Graf, Kristof
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion molecules Adult Aged Biopsy dilated cardiomyopathy Echocardiography Electrocardiography Female heart failure Heart Failure - metabolism Hemodynamics - physiology Humans Immunohistochemistry Male Middle Aged myocardial biopsy Myocardium - metabolism Myocardium - pathology Osteopontin Severity of Illness Index Sialoglycoproteins - biosynthesis Statistics as Topic Stroke Volume - physiology
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