Cryotherapy in the treatment of liver metastases from colorectal cancer

Although hepatic resection remains the treatment of choice for metastatic disease to the liver from colorectal cancer, the procedure is only possible for approximately 10% of patients. Ninety percent of patients with liver metastases ultimately die of liver failure. Thus, attention has turned to other, locoregional techniques that may be used alone or in conjunction with resection to increase the eligibility for some type of surgical, potentially curative treatment. One such option is cryotherapy. This review provides technical, physiologic, and outcome information regarding this technique. Semin Oncol 29:183-191. Copyright 2002, Elsevier Science (USA). All rights reserved.