Sequential MRI in a case of Creutzfeldt-Jakob disease

A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain b...

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Veröffentlicht in:	Neuroradiology 2002-03, Vol.44 (3), p.223-226
Hauptverfasser:	TRIBL, G. G, STRASSER, G, ZEITLHOFER, J, ASENBAUM, S, JARIUS, C, WESSELY, P, PRAYER, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain - pathology Contrast Media Creutzfeldt-Jakob Syndrome - diagnosis Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Electroencephalography Gadolinium DTPA Humans Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Medical sciences Middle Aged Neurology Time Factors
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Beschreibung
Zusammenfassung:	A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease (CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
ISSN:	0028-3940 1432-1920
DOI:	10.1007/s002340100695