Autonomic neuropathy in streptozotocin diabetic rats: effect of acetyl- l-carnitine
The present study was designed to characterize cardiac autonomic neuropathy in streptozotocin-induced (45 mg/kg i.v.) diabetic rat by analysis of heart rate variability (HRV), and to assess, in this model, the effects of treatment with acetyl- l-carnitine (ALC). Heart rate was reduced in diabetic ra...
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Veröffentlicht in: | Diabetes research and clinical practice 2002-06, Vol.56 (3), p.173-180 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The present study was designed to characterize cardiac autonomic neuropathy in streptozotocin-induced (45 mg/kg i.v.) diabetic rat by analysis of heart rate variability (HRV), and to assess, in this model, the effects of treatment with acetyl-
l-carnitine (ALC). Heart rate was reduced in diabetic rats (332±22 vs. 411±35 beat per min;
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ISSN: | 0168-8227 1872-8227 |
DOI: | 10.1016/S0168-8227(01)00375-8 |