Scale-up of erythritol production by an osmophilic mutant of Candida magnoliae

Erythritol production by an osmophilic mutant of Candida magnoliae was performed in fermentations of up 50 l to develop an optimized commercial process. By simultaneous feeding glucose and yeast extract, erythritol productivity of 1.2 g l(-1) h(-1) was reached giving 200 g erythritol l(-1) with a yi...

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Veröffentlicht in:	Biotechnology letters 2003-12, Vol.25 (24), p.2103-2105
Hauptverfasser:	KOH, Eun-Sung, LEE, Tae-Hee, LEE, Do-Yup, KIM, Hyo-Jin, RYU, Yeon-Woo, SEO, Jin-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bioreactors - microbiology Biotechnology Candida - cytology Candida - genetics Candida - growth & development Candida - metabolism Candida magnoliae Cell Culture Techniques - methods Cell Division - physiology Erythritol - biosynthesis Erythritol - genetics Fundamental and applied biological sciences. Psychology Glucose - metabolism Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology Microbiology Mutation Osmosis - physiology Pilot Projects Quality Control Yeasts
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Zusammenfassung:	Erythritol production by an osmophilic mutant of Candida magnoliae was performed in fermentations of up 50 l to develop an optimized commercial process. By simultaneous feeding glucose and yeast extract, erythritol productivity of 1.2 g l(-1) h(-1) was reached giving 200 g erythritol l(-1) with a yield of 0.43 g g(-1).
ISSN:	0141-5492 1573-6776
DOI:	10.1023/B:BILE.0000007076.64338.ce