Microcirculatory effects of pulsed electromagnetic fields

Purpose: Pulsed electromagnetic fields (PEMF) are used clinically to expedite healing of fracture non-unions, however, the mechanism of action by which PEMF stimulation is effective is unknown. The current study examined the acute effects of PEMF stimulation on arteriolar microvessel diameters in th...

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Veröffentlicht in:	Journal of orthopaedic research 2004, Vol.22 (1), p.80-84
Hauptverfasser:	Smith, Thomas L, Wong-Gibbons, Donna, Maultsby, Jane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Electric Impedance Electromagnetic Fields Male Microcirculation Microcirculation - physiology Microcirculation - radiation effects Muscle, Skeletal - blood supply PEMF Rats Rats, Sprague-Dawley Vascular mechanisms Vasodilation - physiology Vasodilation - radiation effects
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Zusammenfassung:	Purpose: Pulsed electromagnetic fields (PEMF) are used clinically to expedite healing of fracture non-unions, however, the mechanism of action by which PEMF stimulation is effective is unknown. The current study examined the acute effects of PEMF stimulation on arteriolar microvessel diameters in the rat cremaster muscle. The study hypothesis was that PEMF would increase arteriolar diameters, a potential mechanism involved in the healing process. Methods: Local PEMF stimulation/sham stimulation of 2 or 60 min duration was delivered to the cremaster muscle of anesthetized rats. Arteriolar diameters were measured before and after stimulation/sham stimulation using intravital microscopy. Systemic hemodynamics also were monitored during PEMF stimulation. Results: Local PEMF stimulation produced significant ( p
ISSN:	0736-0266 1554-527X
DOI:	10.1016/S0736-0266(03)00157-8