Changes in human knee ligament stiffness secondary to osteoarthritis

Stiffness of the medial (MCL) and lateral (LCL) collateral ligaments was compared between a group of 10 patients undergoing total knee arthroplasty for varus degenerative osteoarthritis (OAP), a group of 10 osteoarthritic cadaveric knees (OAC), and a group of 10 non-osteoarthritic cadaveric knees (NOA). A load–elongation curve was obtained for the medial and lateral compartments of each knee using an instrumented Moreland spreader. A strain gage (SG) was attached to the spreader handle and strain was calibrated to load applied against the spread distance. In extension, medial compartment stiffness of the OAP, OAC, and NOA groups was 60.7±16, 52.8±9.3 and 21.4±5.0 N/mm, respectively. Lateral compartment stiffness in extension was 29.2±9.2, 33.3±10.3 and 19.5±5.3 N/mm, for OAP, OAC, and NOA, respectively. Differences in stiffness between the OAP and OAC groups were not statistically significant ( p>0.05). However, the osteoarthritic groups (OAP and OAC) demonstrated a statistically significantly ( p