Targeted Proteomic Profiling of Renal Na+ Transporter and Channel Abundances in Angiotensin II Type 1a Receptor Knockout Mice

The renal tubule transporters responsible for Na and water transport along the nephron have been identified and cloned, permitting comprehensive analysis of transporter protein abundance changes in complex physiological models by using a “targeted proteomics” approach. Here, we apply this approach t...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2002-02, Vol.39 (2, Part 2 Suppl), p.470-473
Hauptverfasser:	Brooks, Heddwen L, Allred, Alicia J, Beutler, Kathleen T, Coffman, Thomas M, Knepper, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - metabolism Animals Kidney - metabolism Mice Mice, Knockout Proteome Receptor, Angiotensin, Type 1 Receptors, Angiotensin - deficiency Receptors, Angiotensin - genetics Receptors, Angiotensin - metabolism Sodium - metabolism Sodium Channels - metabolism
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