Pressure-induced formation of a solvate of paracetamol

Pressure-induced formation of a solvate of paracetamol

Recrystallisation of paracetamol from a solution in methanol at a pressure of 0.62 GPa gives a new 1:1 solvate that has been characterised by single crystal X-ray diffraction.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2003-12 (24), p.3004-3005
Hauptverfasser: Fabbiani, Francesca P A, Allan, David R, Dawson, Alice, David, William I F, McGregor, Pamela A, Oswald, Iain D H, Parsons, Simon, Pulham, Colin R
Format: Artikel
Sprache:eng
Schlagworte:
Acetaminophen - chemistry
Hydrogen Bonding
Methanol - chemistry
Pressure
Solubility
X-Ray Diffraction
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Beschreibung
Zusammenfassung:Recrystallisation of paracetamol from a solution in methanol at a pressure of 0.62 GPa gives a new 1:1 solvate that has been characterised by single crystal X-ray diffraction.
ISSN:1359-7345
1364-548X
DOI:10.1039/b310394c