Involvement of beta-adrenoceptors in a central regulation of the ovarian progesterone release in rats

The intracerebroventricular (i.c.v.) injection of epinephrine modifies ovarian progesterone (P) release in rats on diestrus day 2 (D2). To investigate the characteristic of a central adrenergic effect on the ovarian P release on D2. Also, the function of the superior ovarian nerve (SON) is re-examin...

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Veröffentlicht in:	Neuro-endocrinology letters 2002-02, Vol.23 (1), p.27-31
Hauptverfasser:	De Bortoli, Miguel Angel, Garraza, Marisa Hilda, Aguado, Luis Inocencio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - administration & dosage Adrenergic alpha-Agonists - pharmacology Adrenergic alpha-Antagonists - administration & dosage Adrenergic alpha-Antagonists - pharmacology Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - pharmacology Adrenergic beta-Antagonists - administration & dosage Adrenergic beta-Antagonists - pharmacology Animals Brain - physiology Female Injections, Intraventricular Isoproterenol - administration & dosage Isoproterenol - pharmacology Ovary - blood supply Ovary - metabolism Phentolamine - administration & dosage Phentolamine - pharmacology Phenylephrine - administration & dosage Phenylephrine - pharmacology Progesterone - blood Progesterone - metabolism Propranolol - administration & dosage Propranolol - pharmacology Rats Rats, Inbred Strains Receptors, Adrenergic, beta - physiology Time Factors Veins
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Zusammenfassung:	The intracerebroventricular (i.c.v.) injection of epinephrine modifies ovarian progesterone (P) release in rats on diestrus day 2 (D2). To investigate the characteristic of a central adrenergic effect on the ovarian P release on D2. Also, the function of the superior ovarian nerve (SON) is re-examined. P concentrations were measured using radioimmunoassay techniques. The i.c.v. injection of 5 mg isoproterenol (beta-adrenergic agonist) in SON-intact rats on D2, decreased the P levels in ovarian vein blood from 1 to 25 min after injection (p
ISSN:	0172-780X