Macrocyclic diterpenes from Euphorbia nivulia
The latex of Euphorbia nivulia afforded two ingol diterpenes 3,12-diacetyl-8-benzoylingol (4) and 3,12-diacetyl-7-benzoyl-8-nicotinylingol (5) along with three known ingol diterpenes 1, 2,and 3, and two known triterpenes cycloart-25-en-3beta-ol and cyclonivulinol. Their structures have been assigned...
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Veröffentlicht in: | Phytochemistry (Oxford) 2002-02, Vol.59 (3), p.331-335 |
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container_title | Phytochemistry (Oxford) |
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creator | RAVIKANTH, V NIRANJAN REDDY, V. L PRABHAKAR RAO, T DIWAN, P. V RAMAKRISHNA, S VENKATESWARLU, Y |
description | The latex of Euphorbia nivulia afforded two ingol diterpenes 3,12-diacetyl-8-benzoylingol (4) and 3,12-diacetyl-7-benzoyl-8-nicotinylingol (5) along with three known ingol diterpenes 1, 2,and 3, and two known triterpenes cycloart-25-en-3beta-ol and cyclonivulinol. Their structures have been assigned on the basis of their structural data as well as their acetylated products. The diterpenes 1-5 were tested for the LPS induced PGE(2) inhibition activity. |
doi_str_mv | 10.1016/S0031-9422(01)00461-7 |
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The diterpenes 1-5 were tested for the LPS induced PGE(2) inhibition activity.</description><identifier>ISSN: 0031-9422</identifier><identifier>EISSN: 1873-3700</identifier><identifier>DOI: 10.1016/S0031-9422(01)00461-7</identifier><identifier>PMID: 11830142</identifier><language>eng</language><publisher>Amsterdam: Elsevier</publisher><subject>Biological and medical sciences ; Chemical constitution ; Dinoprostone - antagonists & inhibitors ; Diterpenes - chemistry ; Diterpenes - isolation & purification ; Diterpenes - pharmacology ; Euphorbia - chemistry ; Fundamental and applied biological sciences. Psychology ; General pharmacology ; Humans ; Magnetic Resonance Spectroscopy ; Medical sciences ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. 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The diterpenes 1-5 were tested for the LPS induced PGE(2) inhibition activity.</description><subject>Biological and medical sciences</subject><subject>Chemical constitution</subject><subject>Dinoprostone - antagonists & inhibitors</subject><subject>Diterpenes - chemistry</subject><subject>Diterpenes - isolation & purification</subject><subject>Diterpenes - pharmacology</subject><subject>Euphorbia - chemistry</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. 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The diterpenes 1-5 were tested for the LPS induced PGE(2) inhibition activity.</abstract><cop>Amsterdam</cop><pub>Elsevier</pub><pmid>11830142</pmid><doi>10.1016/S0031-9422(01)00461-7</doi><tpages>5</tpages></addata></record> |
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subjects | Biological and medical sciences Chemical constitution Dinoprostone - antagonists & inhibitors Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Euphorbia - chemistry Fundamental and applied biological sciences. Psychology General pharmacology Humans Magnetic Resonance Spectroscopy Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant physiology and development Triterpenes - chemistry Triterpenes - isolation & purification |
title | Macrocyclic diterpenes from Euphorbia nivulia |
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