Macrocyclic diterpenes from Euphorbia nivulia

The latex of Euphorbia nivulia afforded two ingol diterpenes 3,12-diacetyl-8-benzoylingol (4) and 3,12-diacetyl-7-benzoyl-8-nicotinylingol (5) along with three known ingol diterpenes 1, 2,and 3, and two known triterpenes cycloart-25-en-3beta-ol and cyclonivulinol. Their structures have been assigned...

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Veröffentlicht in:Phytochemistry (Oxford) 2002-02, Vol.59 (3), p.331-335
Hauptverfasser: RAVIKANTH, V, NIRANJAN REDDY, V. L, PRABHAKAR RAO, T, DIWAN, P. V, RAMAKRISHNA, S, VENKATESWARLU, Y
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container_end_page 335
container_issue 3
container_start_page 331
container_title Phytochemistry (Oxford)
container_volume 59
creator RAVIKANTH, V
NIRANJAN REDDY, V. L
PRABHAKAR RAO, T
DIWAN, P. V
RAMAKRISHNA, S
VENKATESWARLU, Y
description The latex of Euphorbia nivulia afforded two ingol diterpenes 3,12-diacetyl-8-benzoylingol (4) and 3,12-diacetyl-7-benzoyl-8-nicotinylingol (5) along with three known ingol diterpenes 1, 2,and 3, and two known triterpenes cycloart-25-en-3beta-ol and cyclonivulinol. Their structures have been assigned on the basis of their structural data as well as their acetylated products. The diterpenes 1-5 were tested for the LPS induced PGE(2) inhibition activity.
doi_str_mv 10.1016/S0031-9422(01)00461-7
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Biological and medical sciences
Chemical constitution
Dinoprostone - antagonists & inhibitors
Diterpenes - chemistry
Diterpenes - isolation & purification
Diterpenes - pharmacology
Euphorbia - chemistry
Fundamental and applied biological sciences. Psychology
General pharmacology
Humans
Magnetic Resonance Spectroscopy
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant physiology and development
Triterpenes - chemistry
Triterpenes - isolation & purification
title Macrocyclic diterpenes from Euphorbia nivulia
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