Meiotic chromosomes as templates for microdissection

As templates for chromosome microdissection, meiotic cells offer several advantages over mitotic cells. The pairing of homologous chromosomes at the metaphase plate of the first meiotic division allows the simultaneous isolation of two copies of the same chromosome, and the sex chromosomes are easy...

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Veröffentlicht in:	Chromosome research 2002, Vol.10 (1), p.45-48
Hauptverfasser:	Christian, Allen T, Pattee, Melissa S, Marchetti, Francesco
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosomes - genetics Chromosomes - ultrastructure Dissection - methods In Situ Hybridization, Fluorescence Male Meiosis Mice Mice, Inbred Strains Templates, Genetic X Chromosome Y Chromosome Yeast
Online-Zugang:	Volltext
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Zusammenfassung:	As templates for chromosome microdissection, meiotic cells offer several advantages over mitotic cells. The pairing of homologous chromosomes at the metaphase plate of the first meiotic division allows the simultaneous isolation of two copies of the same chromosome, and the sex chromosomes are easy to identify in male meiotic cells. We report on a method for making fluorescence in-situ hybridization (FISH) probes from dissected meiotic chromosomes.
ISSN:	0967-3849 1573-6849
DOI:	10.1023/A:1014266010522