From stem cells to prion signalling

A strategy based upon the introduction of an adenovirus-SV40 plasmid into multipotential cells was designed to immortalize clones displaying properties of lineage stem cells. The murine 1C11 cell line behaves as a neuroepithelial progenitor. Upon appropriate induction, almost 100 % of 1C11 precursor...

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Veröffentlicht in:	Comptes rendus. Biologies 2002, Vol.325 (1), p.9-15
Hauptverfasser:	Kellermann, Odile, Lafay-Chebassier, Claire, Ermonval, Myriam, Lehmann, Sylvain, Mouillet-Richard, Sophie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenovirus Animals Caveolin 1 Caveolins - metabolism Cell Differentiation Cell Line Cell Line, Transformed cellules souches différenciation neuronale Gene Expression lineage stem cells Mice neuronal differentiation Neurons - metabolism prion Prions - genetics Prions - physiology Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-fyn PrPC Proteins - genetics PrPC Proteins - physiology Signal Transduction signalisation Simian virus 40 Simian virus 40 - genetics Stem Cells - metabolism Transfection
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