Plant molecular diversity and applications to genomics

Plant molecular diversity and applications to genomics

Surveys of nucleotide diversity are beginning to show how genomes have been shaped by evolution. Nucleotide diversity is also being used to discover the function of genes through the mapping of quantitative trait loci (QTL) in structured populations, the positional cloning of strong QTL, and associa...

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Veröffentlicht in:Current Opinion in Plant Biology 2002-04, Vol.5 (2), p.107-111
Hauptverfasser: Buckler, Edward S, Thornsberry, Jeffry M
Format: Artikel
Sprache:eng
Schlagworte:
Arabidopsis
association mapping
Chromosome Mapping
Evolution, Molecular
genetic diversity
Genetic Variation
Genome, Plant
Genomics
linkage disequilibrium
maize
Phenotype
Plants - genetics
population structure
positional cloning
Quantitative Trait, Heritable
selection
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Zusammenfassung:Surveys of nucleotide diversity are beginning to show how genomes have been shaped by evolution. Nucleotide diversity is also being used to discover the function of genes through the mapping of quantitative trait loci (QTL) in structured populations, the positional cloning of strong QTL, and association mapping. High-throughput genotyping and association tests can resolve the contributions of individual genes to phenotype in natural populations; new statistical strategies filter data efficiently to prevent false associations.
ISSN:1369-5266
1879-0356
DOI:10.1016/S1369-5266(02)00238-8