The burden of amyloidosis on the gastrointestinal tract of an ankylosing spondylitis patient

We present a 26-year-old man with edema, ascites and bloody diarrhea that later proved to be due to gastrointestinal and renal amyloidosis. Interestingly, he was also diagnosed as having ankylosing spondylitis,-possibly after a delay of 12 years. The obscure diagnosis and challenging treatment of se...

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Veröffentlicht in:	Clinical rheumatology 2003-12, Vol.22 (6), p.440-442
Hauptverfasser:	Ozçakar, Levent, Köklü, Seyfettin, Kaymak, Bayram, Kuran, Sedef, Sakaoğullari, Zişan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amyloidosis - complications Amyloidosis - drug therapy Amyloidosis - pathology Arthritis Biopsy, Needle Colchicine - administration & dosage Colonoscopy Disease Progression Drug Therapy, Combination Fatal Outcome Gastrointestinal Diseases - complications Gastrointestinal Diseases - drug therapy Gastrointestinal Diseases - pathology Humans Immunohistochemistry Male Melphalan - administration & dosage Risk Assessment Spondylitis, Ankylosing - complications Spondylitis, Ankylosing - diagnosis Spondylitis, Ankylosing - therapy
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Zusammenfassung:	We present a 26-year-old man with edema, ascites and bloody diarrhea that later proved to be due to gastrointestinal and renal amyloidosis. Interestingly, he was also diagnosed as having ankylosing spondylitis,-possibly after a delay of 12 years. The obscure diagnosis and challenging treatment of secondary amyloidosis are further discussed.
ISSN:	0770-3198 1434-9949
DOI:	10.1007/s10067-003-0755-9