Strategies for Heterocyclic Construction via Novel Multicomponent Reactions Based on Isocyanides and Nucleophilic Carbenes

This Account focuses mainly on our recent endeavors in the area of multicomponent reactions (MCRs) involving zwitterionic species generated by the addition of isocyanides and nucleophilic carbenes such as dimethoxycarbene and N-heterocyclic carbenes to activated alkynes. The strategy employed encomp...

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Veröffentlicht in:	Accounts of chemical research 2003-12, Vol.36 (12), p.899-907
Hauptverfasser:	Nair, Vijay, Rajesh, C, Vinod, A. U, Bindu, S, Sreekanth, A. R, Mathen, J. S, Balagopal, Lakshmi
Format:	Artikel
Sprache:	eng
Schlagworte:	Combinatorial Chemistry Techniques - methods Cyanides - chemistry Cyclization Heterocyclic Compounds - chemical synthesis Heterocyclic Compounds - chemistry Hydrocarbons Methane - analogs & derivatives Methane - chemistry Models, Chemical Molecular Conformation Molecular Structure Stereoisomerism
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