Small bowel transit and gastric emptying after biliodigestive anastomosis using the uncut jejunal loop

The Roux-en-Y loop is an effective procedure for biliodigestive drainage. However, up to 15% of patients suffer from postoperative cholangitis or blind loop syndrome. A new technique to prevent motility abnormalities has been developed. Male Lewis rats were used to compare gastric emptying and trans...

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Veröffentlicht in:The American journal of surgery 2003-12, Vol.186 (6), p.747-751
Hauptverfasser: Klaus, Alexander, Hinder, Ronald A, Nguyen, Justin H.H, Nelson, Kevin L
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Sprache:eng
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Zusammenfassung:The Roux-en-Y loop is an effective procedure for biliodigestive drainage. However, up to 15% of patients suffer from postoperative cholangitis or blind loop syndrome. A new technique to prevent motility abnormalities has been developed. Male Lewis rats were used to compare gastric emptying and transit in the small bowel after either a standard Roux-en-Y anastomosis or a new biliodigestive anastomosis technique which involves creating an “uncut” jejunal loop with luminal occlusion. Unoperated rats served as controls. 99Technetium HIDA and 111Indium-tagged amberlite were respectively used to investigate small bowel transit and gastric emptying. Histopathology showed distinctive abnormalities only in the liver of conventional Roux-en-Y animals. No recanalization of the obliterated gut lumen occurred in uncut Roux animals. Distribution of 99Tc-HIDA and 111In showed were similar in both groups. Gastric emptying is slowed in both groups. The uncut proximal jejunum loop is a good alternative to the conventional Roux-en-Y loop and showed preserved small bowel motility and adequate jejunal transit. Gastric emptying is slowed in both groups.
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2003.08.025