Identifying patient and physician characteristics that affect compliance with antihypertensive medications

Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics...

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Veröffentlicht in:Journal of clinical pharmacy and therapeutics 2002-02, Vol.27 (1), p.47-56
Hauptverfasser: Ren, X. S., Kazis, L. E., Lee, A., Zhang, H., Miller, D. R.
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container_issue 1
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container_title Journal of clinical pharmacy and therapeutics
container_volume 27
creator Ren, X. S.
Kazis, L. E.
Lee, A.
Zhang, H.
Miller, D. R.
description Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics that may influence compliance with antihypertensive medications. Method: We used pharmacy records within the Veterans Health Administration, a database which included 1292 patients and 656 physicians over a 2‐year time period from April 1, 1996, to April 1, 1998. The level of compliance with antihypertensive medications was assessed using a measure developed for this purpose within the Administration. Three separate ordinary least squares regression models were conducted to ascertain the effects of patient and physician characteristics on compliance. Results: Despite the importance of compliance in the clinical management of hypertension, poor compliance with antihypertensive drug treatment was still widespread. Patients who were younger and less active in their treatment decisions tended to be less compliant (P 
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S. ; Kazis, L. E. ; Lee, A. ; Zhang, H. ; Miller, D. R.</creator><creatorcontrib>Ren, X. S. ; Kazis, L. E. ; Lee, A. ; Zhang, H. ; Miller, D. R.</creatorcontrib><description>Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics that may influence compliance with antihypertensive medications. Method: We used pharmacy records within the Veterans Health Administration, a database which included 1292 patients and 656 physicians over a 2‐year time period from April 1, 1996, to April 1, 1998. The level of compliance with antihypertensive medications was assessed using a measure developed for this purpose within the Administration. Three separate ordinary least squares regression models were conducted to ascertain the effects of patient and physician characteristics on compliance. Results: Despite the importance of compliance in the clinical management of hypertension, poor compliance with antihypertensive drug treatment was still widespread. Patients who were younger and less active in their treatment decisions tended to be less compliant (P &lt; 0·05 and 0·05, respectively). Health care providers who were older, residents in speciality care, and physicians (as compared with non‐physicians) had patients who were also less likely to be compliant (P &lt; 0·01, 0·01, and 0·05, respectively). Conclusion: These findings suggest that in order to increase the effectiveness of medical care for hypertension, it is important to improve compliance with antihypertensive agents.</description><identifier>ISSN: 0269-4727</identifier><identifier>EISSN: 1365-2710</identifier><identifier>DOI: 10.1046/j.1365-2710.2002.00387.x</identifier><identifier>PMID: 11846861</identifier><identifier>CODEN: JCPTED</identifier><language>eng</language><publisher>Oxford UK: Blackwell Science Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Aged, 80 and over ; Analysis. Health state ; Antihypertensive agents ; Antihypertensive Agents - therapeutic use ; antihypertensive medications ; Biological and medical sciences ; Cardiovascular system ; compliance ; Decision Making ; Epidemiology ; Female ; General aspects ; Health Care Surveys ; Humans ; hypertension ; Hypertension - drug therapy ; Male ; Medical sciences ; Medicine ; Middle Aged ; patient and physician characteristics ; Patient Compliance ; Patient Education as Topic ; Pharmacology. Drug treatments ; Physician's Role ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Retrospective Studies ; Specialization</subject><ispartof>Journal of clinical pharmacy and therapeutics, 2002-02, Vol.27 (1), p.47-56</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright Blackwell Scientific Publications Ltd. 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S.</creatorcontrib><creatorcontrib>Kazis, L. E.</creatorcontrib><creatorcontrib>Lee, A.</creatorcontrib><creatorcontrib>Zhang, H.</creatorcontrib><creatorcontrib>Miller, D. R.</creatorcontrib><title>Identifying patient and physician characteristics that affect compliance with antihypertensive medications</title><title>Journal of clinical pharmacy and therapeutics</title><addtitle>J Clin Pharm Ther</addtitle><description>Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics that may influence compliance with antihypertensive medications. Method: We used pharmacy records within the Veterans Health Administration, a database which included 1292 patients and 656 physicians over a 2‐year time period from April 1, 1996, to April 1, 1998. The level of compliance with antihypertensive medications was assessed using a measure developed for this purpose within the Administration. Three separate ordinary least squares regression models were conducted to ascertain the effects of patient and physician characteristics on compliance. Results: Despite the importance of compliance in the clinical management of hypertension, poor compliance with antihypertensive drug treatment was still widespread. Patients who were younger and less active in their treatment decisions tended to be less compliant (P &lt; 0·05 and 0·05, respectively). Health care providers who were older, residents in speciality care, and physicians (as compared with non‐physicians) had patients who were also less likely to be compliant (P &lt; 0·01, 0·01, and 0·05, respectively). 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Health state</subject><subject>Antihypertensive agents</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>antihypertensive medications</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>compliance</subject><subject>Decision Making</subject><subject>Epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>Health Care Surveys</subject><subject>Humans</subject><subject>hypertension</subject><subject>Hypertension - drug therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Middle Aged</subject><subject>patient and physician characteristics</subject><subject>Patient Compliance</subject><subject>Patient Education as Topic</subject><subject>Pharmacology. Drug treatments</subject><subject>Physician's Role</subject><subject>Public health. Hygiene</subject><subject>Public health. 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Hygiene-occupational medicine</topic><topic>Retrospective Studies</topic><topic>Specialization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ren, X. S.</creatorcontrib><creatorcontrib>Kazis, L. E.</creatorcontrib><creatorcontrib>Lee, A.</creatorcontrib><creatorcontrib>Zhang, H.</creatorcontrib><creatorcontrib>Miller, D. 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E.</au><au>Lee, A.</au><au>Zhang, H.</au><au>Miller, D. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identifying patient and physician characteristics that affect compliance with antihypertensive medications</atitle><jtitle>Journal of clinical pharmacy and therapeutics</jtitle><addtitle>J Clin Pharm Ther</addtitle><date>2002-02</date><risdate>2002</risdate><volume>27</volume><issue>1</issue><spage>47</spage><epage>56</epage><pages>47-56</pages><issn>0269-4727</issn><eissn>1365-2710</eissn><coden>JCPTED</coden><abstract>Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics that may influence compliance with antihypertensive medications. Method: We used pharmacy records within the Veterans Health Administration, a database which included 1292 patients and 656 physicians over a 2‐year time period from April 1, 1996, to April 1, 1998. The level of compliance with antihypertensive medications was assessed using a measure developed for this purpose within the Administration. Three separate ordinary least squares regression models were conducted to ascertain the effects of patient and physician characteristics on compliance. Results: Despite the importance of compliance in the clinical management of hypertension, poor compliance with antihypertensive drug treatment was still widespread. Patients who were younger and less active in their treatment decisions tended to be less compliant (P &lt; 0·05 and 0·05, respectively). Health care providers who were older, residents in speciality care, and physicians (as compared with non‐physicians) had patients who were also less likely to be compliant (P &lt; 0·01, 0·01, and 0·05, respectively). Conclusion: These findings suggest that in order to increase the effectiveness of medical care for hypertension, it is important to improve compliance with antihypertensive agents.</abstract><cop>Oxford UK</cop><pub>Blackwell Science Ltd</pub><pmid>11846861</pmid><doi>10.1046/j.1365-2710.2002.00387.x</doi><tpages>10</tpages></addata></record>
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subjects Adult
Age Factors
Aged
Aged, 80 and over
Analysis. Health state
Antihypertensive agents
Antihypertensive Agents - therapeutic use
antihypertensive medications
Biological and medical sciences
Cardiovascular system
compliance
Decision Making
Epidemiology
Female
General aspects
Health Care Surveys
Humans
hypertension
Hypertension - drug therapy
Male
Medical sciences
Medicine
Middle Aged
patient and physician characteristics
Patient Compliance
Patient Education as Topic
Pharmacology. Drug treatments
Physician's Role
Public health. Hygiene
Public health. Hygiene-occupational medicine
Retrospective Studies
Specialization
title Identifying patient and physician characteristics that affect compliance with antihypertensive medications
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