Identifying patient and physician characteristics that affect compliance with antihypertensive medications

Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics...

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Veröffentlicht in:Journal of clinical pharmacy and therapeutics 2002-02, Vol.27 (1), p.47-56
Hauptverfasser: Ren, X. S., Kazis, L. E., Lee, A., Zhang, H., Miller, D. R.
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Sprache:eng
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Zusammenfassung:Background: Compliance with antihypertensive medications is essential to the clinical management of hypertension. Poor compliance with antihypertensive medications has often been associated with treatment failure and disease progression. Objective: To identify patient and prescriber characteristics that may influence compliance with antihypertensive medications. Method: We used pharmacy records within the Veterans Health Administration, a database which included 1292 patients and 656 physicians over a 2‐year time period from April 1, 1996, to April 1, 1998. The level of compliance with antihypertensive medications was assessed using a measure developed for this purpose within the Administration. Three separate ordinary least squares regression models were conducted to ascertain the effects of patient and physician characteristics on compliance. Results: Despite the importance of compliance in the clinical management of hypertension, poor compliance with antihypertensive drug treatment was still widespread. Patients who were younger and less active in their treatment decisions tended to be less compliant (P 
ISSN:0269-4727
1365-2710
DOI:10.1046/j.1365-2710.2002.00387.x