Highly stereoselective synthesis of (-)-monatin, a high-intensity sweetener, using chelation-controlled nitrone cycloaddition

Highly stereoselective synthesis of (-)-monatin, a high-intensity sweetener, using chelation-controlled nitrone cycloaddition

Synthesis of (-)-monatin was achieved by chelation-controlled cycloaddition of nitrone 2 with allyl alcohol 3a in the presence of MgBr2-OEt2.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2003-11 (21), p.2678-2679
Hauptverfasser: Tamura, Osamu, Shiro, Tomoya, Toyao, Atsushi, Ishibashi, Hiroyuki
Format: Artikel
Sprache:eng
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Zusammenfassung:Synthesis of (-)-monatin was achieved by chelation-controlled cycloaddition of nitrone 2 with allyl alcohol 3a in the presence of MgBr2-OEt2.
ISSN:1359-7345
1364-548X
DOI:10.1039/b306791m