Study of total lipid peroxidation and antioxidant activity in pulmonary and mediastinal malignant and benign tumor tissue

Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2003-09, Vol.136 (3), p.283-285
Hauptverfasser:	Korotkina, R N, Spiridonova, O V, Matskevich, G N, Kucheinik, A Sh, Kunitsyn, A G, Vishnevskii, A A, Karelin, A A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Aged Antioxidants - metabolism Antioxidants - pharmacology Bronchial Neoplasms - pathology Cell Line, Tumor Female Glutathione Peroxidase - metabolism Humans Lipid Metabolism Lipid Peroxidation Lipid Peroxides - metabolism Male Middle Aged Neoplasms - metabolism Neoplasms - pathology Pulmonary Alveoli - pathology Thymoma - pathology
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Zusammenfassung:	Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of malignancy: the most pronounced changes were observed in thymoma and adenocarcinoma tissues and minimum changes were found in bronchoalveolar carcinoma tissue.
ISSN:	0007-4888 1573-8221
DOI:	10.1023/B:BEBM.0000008984.82726.2e