Recognition of cell-specific binding of phage display derived peptides using an acoustic wave sensor

ASSLNIA, a peptide selected for murine myofibers using phage display technology, was immobilized onto an acoustic wave sensor. The sensor responded to murine and feline muscle homogenates indicating crosspieces interactions. Kidney, liver, and brain preparations produced insignificant responses.

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Bibliographische Detailangaben
Veröffentlicht in:	Biomolecular engineering 2002-02, Vol.18 (6), p.269-272
Hauptverfasser:	Samoylov, Alexandre M, Samoylova, Tatiana I, Hartell, Mark G, Pathirana, Suram T, Smith, Bruce F, Vodyanoy, Vitaly
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic wave device Acoustics - instrumentation Animals Biosensing Techniques Brain - metabolism Cats Combinatorial Chemistry Techniques In Vitro Techniques Kidney - metabolism Liver - metabolism Mice Molecular Sequence Data Muscle, Skeletal - metabolism Peptide Library Peptides - analysis Peptides - genetics Peptides - metabolism Protein Binding - genetics Skeletal muscle Tissue-specific peptides
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Beschreibung
Zusammenfassung:	ASSLNIA, a peptide selected for murine myofibers using phage display technology, was immobilized onto an acoustic wave sensor. The sensor responded to murine and feline muscle homogenates indicating crosspieces interactions. Kidney, liver, and brain preparations produced insignificant responses.
ISSN:	1389-0344 1878-559X
DOI:	10.1016/S1389-0344(01)00108-3