Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature
To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells. Two case reports and literature review. The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma...
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| Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 2002-02, Vol.109 (2), p.253-257 |
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| creator | Stewart O’Keefe, J Sippy, Brian D Martin, Daniel F Holden, Jeannine T Grossniklaus, Hans E |
| description | To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells.
Two case reports and literature review.
The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma are reviewed.
Clinical observation and cytologic/flow cytometric examination of the infiltrate after AC aspiration.
One patient presented with uveal infiltration, an exudative retinal detachment and an AC infiltrate. Systemic evaluation revealed a follicular lymphoma involving several groups of lymph nodes. The second patient with a known history of abdominal lymphoma was found to have blurred vision, photophobia and an AC infiltrate. Flow cytometric analysis of the AC infiltrate in both patients showed phenotypes consistent with the patients’ systemic lymphomas.
A pseudohypopyon in an adult may represent either the initial manifestation or a later complication of systemic lymphoma, similar to what has been reported in acute leukemia. |
| doi_str_mv | 10.1016/S0161-6420(01)00934-4 |
| format | Article |
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Two case reports and literature review.
The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma are reviewed.
Clinical observation and cytologic/flow cytometric examination of the infiltrate after AC aspiration.
One patient presented with uveal infiltration, an exudative retinal detachment and an AC infiltrate. Systemic evaluation revealed a follicular lymphoma involving several groups of lymph nodes. The second patient with a known history of abdominal lymphoma was found to have blurred vision, photophobia and an AC infiltrate. Flow cytometric analysis of the AC infiltrate in both patients showed phenotypes consistent with the patients’ systemic lymphomas.
A pseudohypopyon in an adult may represent either the initial manifestation or a later complication of systemic lymphoma, similar to what has been reported in acute leukemia.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/S0161-6420(01)00934-4</identifier><identifier>PMID: 11825804</identifier><identifier>CODEN: OPHTDG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abdominal Neoplasms - pathology ; Adult ; Anterior Chamber - pathology ; Biological and medical sciences ; Biomarkers, Tumor - analysis ; Combined Modality Therapy ; Eye Neoplasms - secondary ; Fatal Outcome ; Female ; Flow Cytometry ; Hematologic and hematopoietic diseases ; Humans ; Immunophenotyping ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymphatic Metastasis ; Lymphoma, Follicular - chemistry ; Lymphoma, Follicular - pathology ; Lymphoma, Follicular - therapy ; Lymphoma, Non-Hodgkin - chemistry ; Lymphoma, Non-Hodgkin - pathology ; Lymphoma, Non-Hodgkin - therapy ; Male ; Medical sciences ; Suppuration - pathology</subject><ispartof>Ophthalmology (Rochester, Minn.), 2002-02, Vol.109 (2), p.253-257</ispartof><rights>2002 American Academy of Ophthalmology, Inc.</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0161642001009344$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13454849$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11825804$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stewart O’Keefe, J</creatorcontrib><creatorcontrib>Sippy, Brian D</creatorcontrib><creatorcontrib>Martin, Daniel F</creatorcontrib><creatorcontrib>Holden, Jeannine T</creatorcontrib><creatorcontrib>Grossniklaus, Hans E</creatorcontrib><title>Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells.
Two case reports and literature review.
The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma are reviewed.
Clinical observation and cytologic/flow cytometric examination of the infiltrate after AC aspiration.
One patient presented with uveal infiltration, an exudative retinal detachment and an AC infiltrate. Systemic evaluation revealed a follicular lymphoma involving several groups of lymph nodes. The second patient with a known history of abdominal lymphoma was found to have blurred vision, photophobia and an AC infiltrate. Flow cytometric analysis of the AC infiltrate in both patients showed phenotypes consistent with the patients’ systemic lymphomas.
A pseudohypopyon in an adult may represent either the initial manifestation or a later complication of systemic lymphoma, similar to what has been reported in acute leukemia.</description><subject>Abdominal Neoplasms - pathology</subject><subject>Adult</subject><subject>Anterior Chamber - pathology</subject><subject>Biological and medical sciences</subject><subject>Biomarkers, Tumor - analysis</subject><subject>Combined Modality Therapy</subject><subject>Eye Neoplasms - secondary</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Flow Cytometry</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Immunophenotyping</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymphatic Metastasis</subject><subject>Lymphoma, Follicular - chemistry</subject><subject>Lymphoma, Follicular - pathology</subject><subject>Lymphoma, Follicular - therapy</subject><subject>Lymphoma, Non-Hodgkin - chemistry</subject><subject>Lymphoma, Non-Hodgkin - pathology</subject><subject>Lymphoma, Non-Hodgkin - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Suppuration - pathology</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkU1r3DAQhkVpaTZpf0KLLi3Jwa0-xrLcSwkhSQuBQj_OQpbHrIJtOZK2y_77ajeb9DIzDM_M8M5LyDvOPnHG1edfJfBKgWDnjF8w1kqo4AVZ8RraChouX5LVM3JCTlO6Z4wpJeE1OeFci1ozWJHlcs4YfYjUre3UYaR-HvyYo82YqE0pOF_Knm59XtO0Sxkn7-i4m5Z1mOwX-hOXEDMNA83bQJ1N-7G5pxH_etwe-mukoy9XbN5EfENeDXZM-PaYz8ifm-vfV9-qux-3368u7yoUrcyVbrga2qHR0Dgr676zXIHCvgMQRQQKIUpPq1oP4Di2rdBcCQt1L0RTd0yekY-Pe5cYHjaYspl8cjiOdsawSabhIFrdyAK-P4KbbsLeLNFPNu7M048K8OEI2OTsOEQ7O5_-cxJq0NAW7usjh0VWER9Nch5nh72P6LLpgzecmb175uCe2VtjGDcH9wzIf55Xi6E</recordid><startdate>20020201</startdate><enddate>20020201</enddate><creator>Stewart O’Keefe, J</creator><creator>Sippy, Brian D</creator><creator>Martin, Daniel F</creator><creator>Holden, Jeannine T</creator><creator>Grossniklaus, Hans E</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20020201</creationdate><title>Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature</title><author>Stewart O’Keefe, J ; Sippy, Brian D ; Martin, Daniel F ; Holden, Jeannine T ; Grossniklaus, Hans E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e293t-8716f9f7847ca35dba1646edb442663e222dba8658f4c1e9928162a45d2275b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Abdominal Neoplasms - pathology</topic><topic>Adult</topic><topic>Anterior Chamber - pathology</topic><topic>Biological and medical sciences</topic><topic>Biomarkers, Tumor - analysis</topic><topic>Combined Modality Therapy</topic><topic>Eye Neoplasms - secondary</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Flow Cytometry</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Immunophenotyping</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lymphatic Metastasis</topic><topic>Lymphoma, Follicular - chemistry</topic><topic>Lymphoma, Follicular - pathology</topic><topic>Lymphoma, Follicular - therapy</topic><topic>Lymphoma, Non-Hodgkin - chemistry</topic><topic>Lymphoma, Non-Hodgkin - pathology</topic><topic>Lymphoma, Non-Hodgkin - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Suppuration - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stewart O’Keefe, J</creatorcontrib><creatorcontrib>Sippy, Brian D</creatorcontrib><creatorcontrib>Martin, Daniel F</creatorcontrib><creatorcontrib>Holden, Jeannine T</creatorcontrib><creatorcontrib>Grossniklaus, Hans E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Ophthalmology (Rochester, Minn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stewart O’Keefe, J</au><au>Sippy, Brian D</au><au>Martin, Daniel F</au><au>Holden, Jeannine T</au><au>Grossniklaus, Hans E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature</atitle><jtitle>Ophthalmology (Rochester, Minn.)</jtitle><addtitle>Ophthalmology</addtitle><date>2002-02-01</date><risdate>2002</risdate><volume>109</volume><issue>2</issue><spage>253</spage><epage>257</epage><pages>253-257</pages><issn>0161-6420</issn><eissn>1549-4713</eissn><coden>OPHTDG</coden><abstract>To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells.
Two case reports and literature review.
The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma are reviewed.
Clinical observation and cytologic/flow cytometric examination of the infiltrate after AC aspiration.
One patient presented with uveal infiltration, an exudative retinal detachment and an AC infiltrate. Systemic evaluation revealed a follicular lymphoma involving several groups of lymph nodes. The second patient with a known history of abdominal lymphoma was found to have blurred vision, photophobia and an AC infiltrate. Flow cytometric analysis of the AC infiltrate in both patients showed phenotypes consistent with the patients’ systemic lymphomas.
A pseudohypopyon in an adult may represent either the initial manifestation or a later complication of systemic lymphoma, similar to what has been reported in acute leukemia.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11825804</pmid><doi>10.1016/S0161-6420(01)00934-4</doi><tpages>5</tpages></addata></record> |
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| subjects | Abdominal Neoplasms - pathology Adult Anterior Chamber - pathology Biological and medical sciences Biomarkers, Tumor - analysis Combined Modality Therapy Eye Neoplasms - secondary Fatal Outcome Female Flow Cytometry Hematologic and hematopoietic diseases Humans Immunophenotyping Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphatic Metastasis Lymphoma, Follicular - chemistry Lymphoma, Follicular - pathology Lymphoma, Follicular - therapy Lymphoma, Non-Hodgkin - chemistry Lymphoma, Non-Hodgkin - pathology Lymphoma, Non-Hodgkin - therapy Male Medical sciences Suppuration - pathology |
| title | Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature |
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