Anterior chamber infiltrates associated with systemic lymphoma: Report of two cases and review of the literature

To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells. Two case reports and literature review. The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Ophthalmology (Rochester, Minn.) Minn.), 2002-02, Vol.109 (2), p.253-257
Hauptverfasser: Stewart O’Keefe, J, Sippy, Brian D, Martin, Daniel F, Holden, Jeannine T, Grossniklaus, Hans E
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:To describe the clinicopathologic features of two patients with systemic lymphoma who developed anterior chamber (AC) infiltrates of lymphoma cells. Two case reports and literature review. The clinical and pathologic findings in two patients with AC infiltrates secondary to systemic B-cell lymphoma are reviewed. Clinical observation and cytologic/flow cytometric examination of the infiltrate after AC aspiration. One patient presented with uveal infiltration, an exudative retinal detachment and an AC infiltrate. Systemic evaluation revealed a follicular lymphoma involving several groups of lymph nodes. The second patient with a known history of abdominal lymphoma was found to have blurred vision, photophobia and an AC infiltrate. Flow cytometric analysis of the AC infiltrate in both patients showed phenotypes consistent with the patients’ systemic lymphomas. A pseudohypopyon in an adult may represent either the initial manifestation or a later complication of systemic lymphoma, similar to what has been reported in acute leukemia.
ISSN:0161-6420
1549-4713
DOI:10.1016/S0161-6420(01)00934-4