A Gradient of Single-Channel Conductance in the Cochlea: Tuning the Cochlea's Strings?

A Gradient of Single-Channel Conductance in the Cochlea: Tuning the Cochlea's Strings?

Frequency tuning in the vertebrate cochlea requires a continuously varying amplifier in auditory hair cells. In this issue of Neuron, Ricci et al. show that the mechanosensitive transduction channel, a possible amplifier component, has a single-channel conductance that increases systematically along...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuron 2003-12, Vol.40 (5), p.875-876
Hauptverfasser: Cheung, Eunice L.M, Corey, David P
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Calcium Channels - physiology
Cochlea - physiology
Ears & hearing
Humans
Ion Channels - physiology
Medical research
Signal Transduction - physiology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Frequency tuning in the vertebrate cochlea requires a continuously varying amplifier in auditory hair cells. In this issue of Neuron, Ricci et al. show that the mechanosensitive transduction channel, a possible amplifier component, has a single-channel conductance that increases systematically along the frequency axis of the turtle cochlea.
ISSN:0896-6273
1097-4199
DOI:10.1016/S0896-6273(03)00762-1