Antisense transcripts in the human genome

By a systematic search of vertebrate mRNA sequences, we have identified a surprisingly large number of human antisense transcripts. These data suggest that regulation of gene expression by antisense and double-stranded RNAs could be a common phenomenon in mammalian cells. The identification of large...

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Veröffentlicht in:	Trends in genetics 2002-02, Vol.18 (2), p.63-65
Hauptverfasser:	Lehner, Ben, Williams, Gary, Campbell, R.Duncan, Sanderson, Christopher M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals antisense transcripts Chromosome Mapping Databases, Nucleic Acid DNA Repair DNA, Antisense double-stranded RNA Gene Expression Regulation gene regulation gene silencing Genome, Human Humans Mammals - genetics Proteins - genetics Proteins - metabolism regulatory RNA RNA, Messenger - genetics RNAi
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