Intense exercise has unique effects on both insulin release and its roles in glucoregulation: Implications for diabetes

In intense exercise (>80% VO(2max)), unlike at lesser intensities, glucose is the exclusive muscle fuel. It must be mobilized from muscle and liver glycogen in both the fed and fasted states. Therefore, regulation of glucose production (GP) and glucose utilization (GU) have to be different from e...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2002-02, Vol.51 (2), p.S271-S283
Hauptverfasser:	MARLISS, Errol B, VRANIC, Mladen
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biological transport Blood Glucose - metabolism Diabetes Diabetes Mellitus, Type 2 - metabolism Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Exercise Exercise - physiology Glucose Glucose metabolism Humans Hyperglycemia Insulin Insulin - metabolism Medical sciences Pancreas Pancreatic secretions Physiological aspects Physiological transport Secretions Type 2 diabetes
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Zusammenfassung:	In intense exercise (>80% VO(2max)), unlike at lesser intensities, glucose is the exclusive muscle fuel. It must be mobilized from muscle and liver glycogen in both the fed and fasted states. Therefore, regulation of glucose production (GP) and glucose utilization (GU) have to be different from exercise at
ISSN:	0012-1797 1939-327X
DOI:	10.2337/diabetes.51.2007.S271