Successful pregnancy outcome following 19 consecutive miscarriages: Case report

No cause can be found in 50% of patients with recurrent miscarriage. Recent research has shown that high levels of natural killer (NK) cells within the endometrium may be associated with idiopathic recurrent miscarriage. This case report describes a patient in whom an excessive number of uterine NK...

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Veröffentlicht in:	Human reproduction (Oxford) 2003-12, Vol.18 (12), p.2562-2564
Hauptverfasser:	Quenby, Siobhan, Farquharson, Roy, Young, Michelle, Vince, Gill
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - drug therapy Abortion, Habitual - immunology Abortion, Habitual - pathology Biological and medical sciences Cell Count Female Fundamental and applied biological sciences. Psychology Humans Key words: case report/natural killer cells/prednisolone/recurrent miscarriage Killer Cells, Natural - pathology Mother. Fetoplacental unit. Mammary gland. Milk Prednisolone - administration & dosage Prednisolone - therapeutic use Pregnancy Pregnancy Outcome Pregnancy. Parturition. Lactation Uterus - pathology Vertebrates: reproduction
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Zusammenfassung:	No cause can be found in 50% of patients with recurrent miscarriage. Recent research has shown that high levels of natural killer (NK) cells within the endometrium may be associated with idiopathic recurrent miscarriage. This case report describes a patient in whom an excessive number of uterine NK cells were found. She received preconceptual prednisolone and delivered a live baby. This is a novel observation of untested significance.
ISSN:	0268-1161 1460-2350 1460-2350
DOI:	10.1093/humrep/deg502