Predictors of Plasma Human Immunodeficiency Virus Type 1 RNA Control after Discontinuation of Highly Active Antiretroviral Therapy Initiated at Acute Infection Combined with Structured Treatment Interruptions and Immune-Based Therapies

Thirty patients with acute human immunodeficiency virus (HIV) type 1 infection received a combination of 3 antiretroviral drugs (n=15) or 4 antiretroviral drugs plus hydroxyurea and interleukin-2 (n=15) for 24 months, followed by 1–3 structured therapeutic interruptions (STIs). Viral control, define...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 2003-11, Vol.188 (10), p.1426-1432
Hauptverfasser:	Lafeuillade, A., Poggi, C., Hittinger, G., Counillon, E., Emilie, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS antiretroviral agents Antiretroviral Therapy, Highly Active Biological and medical sciences Blood plasma CD4 Lymphocyte Count DNA DNA, Viral - blood Drug Administration Schedule Female Fundamental and applied biological sciences. Psychology Highly active antiretroviral therapy HIV HIV 1 HIV Infections - blood HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 - genetics HIV/AIDS Human immunodeficiency virus 1 Human viral diseases Humans hydroxyurea Hydroxyurea - administration & dosage Hydroxyurea - therapeutic use Infections Infectious diseases Interleukin-2 - administration & dosage Interleukin-2 - therapeutic use Lymphocytes Male Medical sciences Microbiology Miscellaneous Multivariate Analysis Nucleic Acid Synthesis Inhibitors - administration & dosage Nucleic Acid Synthesis Inhibitors - therapeutic use Pilot Projects Proportional Hazards Models Proviruses - growth & development Proviruses - immunology Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - therapeutic use RNA RNA, Viral - blood Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viremia Virology Virus Replication
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Thirty patients with acute human immunodeficiency virus (HIV) type 1 infection received a combination of 3 antiretroviral drugs (n=15) or 4 antiretroviral drugs plus hydroxyurea and interleukin-2 (n=15) for 24 months, followed by 1–3 structured therapeutic interruptions (STIs). Viral control, defined as maintaining plasma viremia
ISSN:	0022-1899 1537-6613
DOI:	10.1086/379251