Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

Summary Analysis of FcγRIIA alleles in Pakistanis and in Trinidadians of South Asian, African and mixed ancestry revealed no significant differences between Trinidadian South Asians and Pakistanis. H131 homozygotes were more common among Trinidadian South Asians than among Africans and those of mixe...

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Veröffentlicht in:European journal of immunogenetics 2003-10, Vol.30 (5), p.375-379
Hauptverfasser: Carrington, C. V. F., Norman, P. J., Vaughan, R. W., Kondeatis, E., Ramdath, D. D., Hameed, K., Stephens, H. A. F.
Format: Artikel
Sprache:eng
Schlagworte:
Africa
Antigens, CD - genetics
Asia
Gene Frequency
Humans
Polymorphism, Genetic
Receptors, IgG - genetics
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Zusammenfassung:Summary Analysis of FcγRIIA alleles in Pakistanis and in Trinidadians of South Asian, African and mixed ancestry revealed no significant differences between Trinidadian South Asians and Pakistanis. H131 homozygotes were more common among Trinidadian South Asians than among Africans and those of mixed ancestry. Comparison with other populations revealed east–west geographic gradients of allele frequencies.
ISSN:0960-7420
1365-2370
DOI:10.1046/j.1365-2370.2003.00417.x