Encapsulation of deoxyribonucleic acid molecules in silica and hybrid organic-silica gels
The encapsulation of small DNA molecules was attempted in pure silica and in hybrid polyvinyl alcohol-silica gels. The materials which were obtained were examined by nitrogen adsorption, and by 29Si and 31P NMR spectroscopy. The extraction of the DNA molecules from the gels was examined in a buffer...
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Veröffentlicht in: | Journal of materials science. Materials in medicine 2001-01, Vol.12 (1), p.51-55 |
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creator | Pierre, A Bonnet, J Vekris, A Portier, J |
description | The encapsulation of small DNA molecules was attempted in pure silica and in hybrid polyvinyl alcohol-silica gels. The materials which were obtained were examined by nitrogen adsorption, and by 29Si and 31P NMR spectroscopy. The extraction of the DNA molecules from the gels was examined in a buffer aqueous solution as well as in an acidic medium. The results suggested that the DNA molecules remained trapped inside the gels due to a permanent bonding to the gel network. |
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The materials which were obtained were examined by nitrogen adsorption, and by 29Si and 31P NMR spectroscopy. The extraction of the DNA molecules from the gels was examined in a buffer aqueous solution as well as in an acidic medium. The results suggested that the DNA molecules remained trapped inside the gels due to a permanent bonding to the gel network.</description><identifier>ISSN: 0957-4530</identifier><identifier>EISSN: 1573-4838</identifier><identifier>DOI: 10.1023/A:1013857102461</identifier><identifier>PMID: 15348377</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Alcohols ; Biomedical materials ; Deoxyribonucleic acid ; DNA ; Encapsulation ; Gels ; Magnetic resonance spectroscopy ; Materials science ; Molecular chains ; NMR spectroscopy ; Polyvinyl alcohol ; Silica ; Silica gel ; Silicon dioxide</subject><ispartof>Journal of materials science. Materials in medicine, 2001-01, Vol.12 (1), p.51-55</ispartof><rights>Copyright 2001 Kluwer Academic Publishers</rights><rights>Journal of Materials Science: Materials in Medicine is a copyright of Springer, (2001). 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The results suggested that the DNA molecules remained trapped inside the gels due to a permanent bonding to the gel network.</description><subject>Alcohols</subject><subject>Biomedical materials</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Encapsulation</subject><subject>Gels</subject><subject>Magnetic resonance spectroscopy</subject><subject>Materials science</subject><subject>Molecular chains</subject><subject>NMR spectroscopy</subject><subject>Polyvinyl alcohol</subject><subject>Silica</subject><subject>Silica gel</subject><subject>Silicon dioxide</subject><issn>0957-4530</issn><issn>1573-4838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqF0U1LAzEQBuAgiq3VszdZEMTLapJJNom3UuoHFLzowdOSzWZrSjapmy7Yf-8W68WDnoZhHt5hGITOCb4hmMLt9I5gApKLoWMFOUBjwgXkTII8RGOsuMgZBzxCJymtMMZMcX6MRoTDQIQYo7d5MHqdeq83LoYsNllt4-e2c1UMvfHWmUwbV2dt9Nb03qbMhSw574zOdKiz923VDePYLXVwJt9PltanU3TUaJ_s2b5O0Ov9_GX2mC-eH55m00VugPFNbsEKYhvMG1kLw5hQAJxyWhMuhWlUVTUcCmyFaCprJBhlcF1hTKnRIJSCCbr6zl138aO3aVO2LhnrvQ429qkUBBQRwP6FtJCsoGSXeP0nJAwYJoLQHb38RVex78Jwb0mxKIBIOuyfoIu96qvW1uW6c63utuXPG-ALtaeIlw</recordid><startdate>200101</startdate><enddate>200101</enddate><creator>Pierre, A</creator><creator>Bonnet, J</creator><creator>Vekris, A</creator><creator>Portier, J</creator><general>Springer Nature B.V</general><scope>NPM</scope><scope>3V.</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H8D</scope><scope>H8G</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KB.</scope><scope>KR7</scope><scope>L7M</scope><scope>LK8</scope><scope>L~C</scope><scope>L~D</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0W</scope><scope>7TM</scope><scope>7X8</scope></search><sort><creationdate>200101</creationdate><title>Encapsulation of deoxyribonucleic acid molecules in silica and hybrid organic-silica gels</title><author>Pierre, A ; 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subjects | Alcohols Biomedical materials Deoxyribonucleic acid DNA Encapsulation Gels Magnetic resonance spectroscopy Materials science Molecular chains NMR spectroscopy Polyvinyl alcohol Silica Silica gel Silicon dioxide |
title | Encapsulation of deoxyribonucleic acid molecules in silica and hybrid organic-silica gels |
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