Report of three case studies with olanzapine for chronic pain

Olanzapine, an atypical antipsychotic, has broad spectrum psychotropic effects, affecting dopamine receptors 1, 2, and 3, 5-hydroxytryptamine 2A, 5-hydroxytryptamine 2C, muscarinic, alpha-adrenergic, alpha-adrenergic, and histamine H-sites. This unique pharmacologic property allows clinicians to use...

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Veröffentlicht in:The journal of pain 2003-04, Vol.4 (3), p.166-168
Hauptverfasser: Gorski, Eugene D., Willis, Kerry C.
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container_title The journal of pain
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creator Gorski, Eugene D.
Willis, Kerry C.
description Olanzapine, an atypical antipsychotic, has broad spectrum psychotropic effects, affecting dopamine receptors 1, 2, and 3, 5-hydroxytryptamine 2A, 5-hydroxytryptamine 2C, muscarinic, alpha-adrenergic, alpha-adrenergic, and histamine H-sites. This unique pharmacologic property allows clinicians to use the agent as an adjunct for pain control, particularly when the intensity of the pain is exacerbated by dysregulation of neurotransmitters. Three case studies are presented from a suburban family practice setting in which olanzapine has been successfully used to regulate pain perception in adults with chronic pain. [copy ] 2003 by the American Pain Society
doi_str_mv 10.1054/jpai.2003.438
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subjects Analgesics, Non-Narcotic - therapeutic use
Benzodiazepines
Chronic Disease
Female
Humans
Middle Aged
Pain - drug therapy
Pirenzepine - analogs & derivatives
Pirenzepine - therapeutic use
title Report of three case studies with olanzapine for chronic pain
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