Report of three case studies with olanzapine for chronic pain
Olanzapine, an atypical antipsychotic, has broad spectrum psychotropic effects, affecting dopamine receptors 1, 2, and 3, 5-hydroxytryptamine 2A, 5-hydroxytryptamine 2C, muscarinic, alpha-adrenergic, alpha-adrenergic, and histamine H-sites. This unique pharmacologic property allows clinicians to use...
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Veröffentlicht in: | The journal of pain 2003-04, Vol.4 (3), p.166-168 |
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container_title | The journal of pain |
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creator | Gorski, Eugene D. Willis, Kerry C. |
description | Olanzapine, an atypical antipsychotic, has broad spectrum psychotropic effects, affecting dopamine receptors 1, 2, and 3, 5-hydroxytryptamine 2A, 5-hydroxytryptamine 2C, muscarinic, alpha-adrenergic, alpha-adrenergic, and histamine H-sites. This unique pharmacologic property allows clinicians to use the agent as an adjunct for pain control, particularly when the intensity of the pain is exacerbated by dysregulation of neurotransmitters. Three case studies are presented from a suburban family practice setting in which olanzapine has been successfully used to regulate pain perception in adults with chronic pain. [copy ] 2003 by the American Pain Society |
doi_str_mv | 10.1054/jpai.2003.438 |
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subjects | Analgesics, Non-Narcotic - therapeutic use Benzodiazepines Chronic Disease Female Humans Middle Aged Pain - drug therapy Pirenzepine - analogs & derivatives Pirenzepine - therapeutic use |
title | Report of three case studies with olanzapine for chronic pain |
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