Surface modification in microchip electrophoresis

Surface modification in microchip electrophoresis

Different approaches and techniques for surface modification of microfluidic devices applied for microchip electrophoresis are reviewed. The main focus is on the improved electrophoretic separation by reducing analyte‐wall interactions and manipulation of electroosmosis. Approaches and methods for p...

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Veröffentlicht in:Electrophoresis 2003-11, Vol.24 (21), p.3595-3606
Hauptverfasser: Belder, Detlev, Ludwig, Martin
Format: Artikel
Sprache:eng
Schlagworte:
Acrylic Resins
Dynamic coating
Electroosmosis
Electrophoresis - methods
Indicators and Reagents
Microchip
Miniaturization
Miniaturization - methods
Molecular Probe Techniques
Permanent coating
Polymethyl Methacrylate
Review
Surface modification
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Beschreibung
Zusammenfassung:Different approaches and techniques for surface modification of microfluidic devices applied for microchip electrophoresis are reviewed. The main focus is on the improved electrophoretic separation by reducing analyte‐wall interactions and manipulation of electroosmosis. Approaches and methods for permanent and dynamic surface modification of microfluidic devices, manufactured from glass, quartz and also different polymeric substrates, are described.
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.200305648