Rapid and Versatile Synthesis of Functionalized Polyhydroxylated Fragments

Rapid and Versatile Synthesis of Functionalized Polyhydroxylated Fragments

The condensation between a functionalized allylstannane and α-alkoxyaldehydes allows rapid access to complex and selectively protected trihydroxylated synthons. The stereocontrol of this process is strongly dependent upon the nature and the amount of the Lewis acid employed.

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Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2002-01, Vol.4 (1), p.47-50
Hauptverfasser: Leroy, Bernard, Markó, István E
Format: Artikel
Sprache:eng
Schlagworte:
Aldehydes - chemistry
Allyl Compounds - chemistry
Hydroxylation
Indicators and Reagents
Molecular Conformation
Organotin Compounds - chemistry
Stereoisomerism
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Beschreibung
Zusammenfassung:The condensation between a functionalized allylstannane and α-alkoxyaldehydes allows rapid access to complex and selectively protected trihydroxylated synthons. The stereocontrol of this process is strongly dependent upon the nature and the amount of the Lewis acid employed.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol016863u